The protein encoded by this gene is a guanylyl cyclase
found predominantly in photoreceptors in the retina. The encoded
protein is thought to be involved in resynthesis of cGMP after
light activation of the visual signal transduction cascade,
allowing a return to the dark state. This protein is a single-pass
type I membrane protein. Defects in this gene may be a cause of
X-linked retinitis pigmentosa.1) Blackford, A., et al. Cancer Res. 69(8):3681-3688(2009)
Immunogen
This GUCY2F antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 828-856 amino acids from the C-terminal region of human GUCY2F.
Western blot analysis in 293 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.