HBEGF may be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts and smooth muscle but not endothelial cells. It is able to bind EGF receptors with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Immunogen
This HBEGF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-96 amino acids from the Central region of human HBEGF.
Western blot analysis in K562 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.