Western blot analysis of extracts from HeLa cells using HDAC7A (Phospho-Ser155) Antibody. The lane on the right is treated with the antigen-specific peptide.
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.1) Walsh M.J., Submitted (FEB-2000).
Immunogen
HDAC7A (phospho Ser155) antibody was raised against a peptide sequence around phosphorylation site of Serine 155 (T-V-S (p)-E-P) derived from Human HDAC7A.
Western blot analysis of extracts from HeLa cells using HDAC7A (Phospho-Ser155) Antibody. The lane on the right is treated with the antigen-specific peptide.
Application Notes
Western Blot: 1:500~1:1000
Additional Information
Form
Liquid
Storage Instructions
Store antibody at -20˚C for up to one year.
Storage Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.