Application
Antibody used in CHIP on HCT116 Cells.Application
Antibody used in IHC on Human kidney.Application
Antibody used in WB on Human A172 at 1.25 ug/ml.| Product Name | HDAC9 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC9 has sequence homology to members of the histone deacetylase family. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. HDAC9 may play a role in hematopoiesis.Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined.1) Han, A., (2005) J. Mol. Biol. 345 (1), 91-102. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HDAC9. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| HDAC9 antibody can be used for detection of HDAC9 by ELISA at 1:1562500. HDAC9 antibody can be used for detection of HDAC9 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. | |
| Species Reactivity | DogHumanMouse |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | HDAC9 |
|---|---|
| Alternative Names | HDAC9 DKFZp779K1053 HD7 HDAC HDAC7 HDAC7B HDAC9B HDAC9FL HDRP KIAA0744 MITR HD9 HD7b |
| Molecular Weight(MW) | 65 kDa |
Application
Antibody used in CHIP on HCT116 Cells.
Application
Antibody used in IHC on Human kidney.
Application
Antibody used in WB on Human A172 at 1.25 ug/ml.| Positive Control | 1) A172 Cell Lysate |
|---|---|
| Application Notes | HDAC9 antibody can be used for detection of HDAC9 by ELISA at 1:1562500. HDAC9 antibody can be used for detection of HDAC9 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store HDAC9 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
