This gene encodes a member of the group II decarboxylase
family and forms a homodimer that converts L-histidine to histamine
in a pyridoxal phosphate dependent manner. Histamine regulates
several physiologic processes, including neurotransmission, gastric
acid secretion,inflamation, and smooth muscle tone.1) Gervasini, G., et al. Allergy (2010) In press :
Immunogen
This HDC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-178 amino acids from the N-terminal region of human HDC.
Western blot analysis in NCI-H292 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.