Hypermethylated in cancer 1 protein, Hic-1, Zinc finger and BTB domain-containing protein 29, HIC1, ZBTB29
Product description
This gene functions as a growth regulatory and tumor
repressor gene. Hypermethylation or deletion of the region of this
gene have been associated with tumors and the contiguous-gene
syndrome, Miller-Dieker syndrome. Alternative splicing of this gene
results in multiple transcript variants.1) Pehlivan, S., et al. Cancer Genet. Cytogenet. 201(2):128-132(2010)
Immunogen
This HIC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 498-527 amino acids from the C-terminal region of human HIC1.
Western blot analysis in NCI-H292 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.