HIon Channel1 is a transcriptional repressor. HIon Channel1 may act as a tumor suppressor. HIon Channel1 may be involved in development of head, face, limbs and ventral body wall. Defects in HIon Channel1 may be a cause of the facial dysmorphism and additional birth defects (except for lissencephaly) seen in the contiguous gene disorder Miller-Dieker syndrome (MDS), like defective development of the nose, jaws, extremities, gastrointestinal tract, and kidney.1) Chopin, V. (2006) Med Sci (Paris) 22 (1), 54-61.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HIon Channel1.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAWB
HIon Channel1 antibody can be used for detection of HIon Channel1 by ELISA at 1:312500. HIon Channel1 antibody can be used for detection of HIon Channel1 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
HIon Channel1 antibody can be used for detection of HIon Channel1 by ELISA at 1:312500. HIon Channel1 antibody can be used for detection of HIon Channel1 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store HIon Channel1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.