HLA class II histocompatibility antigen, DQ alpha 2 chain, DX alpha chain, HLA class II histocompatibility antigen, DQ(6) alpha chain, HLA-DQA1, MHC class II DQA2, HLA-DQA2, HLA-DXA
Product description
This gene belongs to the HLA class II alpha chain family.
The encoded protein forms a heterodimer with a class II beta chain.
It is located in intracellular vesicles and plays a central role in
the peptide loading of MHC class II molecules by helping to release
the CLIP molecule from the peptide binding site. Class II molecules
are expressed in antigen presenting cells (B lymphocytes, dendritic
cells, macrophages) and are used to present antigenic peptides on
the cell surface to be recognized by CD4 T-cells. [provided by
RefSeq].1) Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16(10):770-777(2010)
Immunogen
This HLA-DQA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-66 amino acids from the Central region of human HLA-DQA2.
HLA class II histocompatibility antigen DQ alpha 2 chain DX alpha chain HLA class II histocompatibility antigen DQ(6) alpha chain HLA-DQA1 MHC class II DQA2 HLA-DQA2 HLA-DXA
Western blot analysis in NCI-H292 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.