Heme oxygenase, an essential enzyme in heme catabolism,
cleaves heme to form biliverdin, which is subsequently converted to
bilirubin by biliverdin reductase, and carbon monoxide, a putative
neurotransmitter. Heme oxygenase activity is induced by its
substrate heme and by various nonheme substances. Heme oxygenase
occurs as 2 isozymes, an inducible heme oxygenase-1 and a
constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme
oxygenase family. Alternative splice variants encoding the same
protein have been identified at this locus.1) Abdel Aziz, M.T., et al. Andrologia 42(4):236-241(2010)
Immunogen
This HMOX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-52 amino acids from the N-terminal region of human HMOX2.
Western blot analysis in Jurkat cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.