Application
Antibody used in WB on Human Jurkat cells at 1.25 ug/ml.Application
Antibody used in IHC on Human Heart at 4.0-8.0 ug/ml.Application
Antibody used in IHC on Human Liver at 4.0-8.0 ug/ml.| Product Name | HNRPD Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HNRPD, P37, AUF1, AUF1A, HNRPD, hnRNPD0 |
| Product description | HNRPD belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants.1) Dhakras, P.S., Am. J. Physiol. Renal Physiol. 290 (2), F313-F318 (2006). |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HNRPD. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| HNRPD antibody can be used for detection of HNRPD by ELISA at 1:62500. HNRPD antibody can be used for detection of HNRPD by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | DogHumanRat |
| Concentration | 1mg/ml |
| Gene Symbol | HNRNPD |
|---|---|
| Alternative Names | HNRPD P37 AUF1 AUF1A HNRPD hnRNPD0 |
| Molecular Weight(MW) | 39 kDa, 31 kDa, 33 kDa, 36 kDa |
Application
Antibody used in WB on Human Jurkat cells at 1.25 ug/ml.
Application
Antibody used in IHC on Human Heart at 4.0-8.0 ug/ml.
Application
Antibody used in IHC on Human Liver at 4.0-8.0 ug/ml.| Positive Control | 1) Cat. No. 1205 - Jurkat Cell Lysate |
|---|---|
| Application Notes | HNRPD antibody can be used for detection of HNRPD by ELISA at 1:62500. HNRPD antibody can be used for detection of HNRPD by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store HNRPD antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
