HNRNPLL is a master regulator of activation-induced
alternative splicing in T cells. In particular, it alters splicing
of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for
T-cell development and activation (Oberdoerffer et al., 2008
[PubMed 18669861]).1) Wu, Z., et al. J. Immunol. 185(1):231-238(2010)
Immunogen
This HNRPLL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-162 amino acids from the N-terminal region of human HNRPLL.
Western blot analysis in T47D cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.