Homeobox protein Hox-A13, Homeobox protein Hox-1J, HOXA13, HOX1J
Product description
In vertebrates, the genes encoding the class of
transcription factors called homeobox genes are found in clusters
named A, B, C, and D on four separate chromosomes. Expression of
these proteins is spatially and temporally regulated during
embryonic development. This gene is part of the A cluster on
chromosome 7 and encodes a DNA-binding transcription factor which
may regulate gene expression, morphogenesis, and differentiation.
Expansion of a polyalanine tract in the encoded protein can cause
hand-foot-uterus syndrome, also known as hand-foot-genital
syndrome.1) Jorgensen, E.M., et al. Fertil. Steril. 94(4):1235-1238(2010)
Immunogen
This HOXA13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 356-383 amino acids from the C-terminal region of human HOXA13.
Western blot analysis in Y79 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.