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HOXB8 Antibody

Catalog Number:OM281241
OM281241
Discount Price
OM281241-100ul
1~2 Week
100ul
OM281241-50ul
50ul
OM281241-20ul
20ul
1~2 Week
Product Profile
Product Name HOXB8 Antibody
Antibody Type Primary Antibodies
Antigen Alias HOXB8, HOX2, HOX2D, Hox-2.4
Product description HOXB8 belongs to the Antp homeobox family. It is a nuclear protein with a homeobox DNA-binding domain. This gene is included in a cluster of homeobox B genes located on chromosome 17. The protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.1) Kosaki, K., (2002) Teratology 65 (2), 50-62.
Immunogen Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HOXB8.
Key Feature
Clonality Polyclonal
Host Species Rabbit
Tested Applications ELISAWB
HOXB8 antibody can be used for detection of HOXB8 by ELISA at 1:312500. HOXB8 antibody can be used for detection of HOXB8 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol HOXB8
Alternative Names HOXB8
HOX2
HOX2D
Hox-2.4
Molecular Weight(MW) 27 kDa
Database Links
Entrez Gene 3218
Protein Accession NP_076921
Application

Application

Antibody used in WB on Human Muscle at 0.2-1 ug/ml.
Positive Control 1) Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate
Application Notes HOXB8 antibody can be used for detection of HOXB8 by ELISA at 1:312500. HOXB8 antibody can be used for detection of HOXB8 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form Liquid
Storage Instructions For short periods of storage (days) store at 4˚C. For longer periods of storage, store HOXB8 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
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