Homeobox protein Hox-D11, Homeobox protein Hox-4F, HOXD11, HOX4F
Product description
This gene belongs to the homeobox family of genes. The
homeobox genes encode a highly conserved family of transcription
factors that play an important role in morphogenesis in all
multicellular organisms. Mammals possess four similar homeobox gene
clusters, HOXA, HOXB, HOXC and HOXD, located on different
chromosomes, consisting of 9 to 11 genes arranged in tandem. This
gene is one of several homeobox HOXD genes located in a cluster on
chromosome 2. Deletions that remove the entire HOXD gene cluster or
the 5' end of this cluster have been associated with severe limb
and genital abnormalities. The product of the mouse Hoxd11 gene
plays a role in forelimb morphogenesis.1) Sugie, Y., et al. Brain Dev. 32(5):356-361(2010)
Immunogen
This HOXD11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from the Central region of human HOXD11.
Western blot analysis in A549 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.