Application
Antibody used in WB on Transfected 293T cell lysates at 0.2-1 ug/ml.| Product Name | HOXD4 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HOXD4, HOX4, HOX4B, HHO.C13, HOX-5.1, Hox-4.2 |
| Product description | HOXD4 belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in determining positional values in developing limb buds. Alternatively spliced variants have been described but their full length nature has not been determined.This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in determining positional values in developing limb buds. Alternatively spliced variants have been described but their full length nature has not been determined.1) Kosaki, K., (2002) Teratology 65 (2), 50-62. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HOXD4. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| HOXD4 antibody can be used for detection of HOXD4 by ELISA at 1:62500. HOXD4 antibody can be used for detection of HOXD4 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | HOXD4 |
|---|---|
| Alternative Names | HOXD4 HOX4 HOX4B HHO.C13 HOX-5.1 Hox-4.2 |
| Molecular Weight(MW) | 28 kDa |
Application
Antibody used in WB on Transfected 293T cell lysates at 0.2-1 ug/ml.| Positive Control | 1) Tranfected 293T Cell Lysate |
|---|---|
| Application Notes | HOXD4 antibody can be used for detection of HOXD4 by ELISA at 1:62500. HOXD4 antibody can be used for detection of HOXD4 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store HOXD4 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
