Histamine is a ubiquitous messenger molecule released from
mast cells, enterochromaffin-like cells, and neurons. Its various
actions are mediated by a family of histamine receptors, which are
a subset of the G-protein coupled receptor superfamily. This gene
encodes a histamine receptor that is predominantly expressed in
haematopoietic cells. The protein is thought to play a role in
inflammation and allergy reponses. Multiple transcript variants
encoding different isoforms have been found for this gene.1) Yu, B., et al. Br. J. Dermatol. 163(5):935-940(2010)
Immunogen
This HRH4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-256 amino acids from the Central region of human HRH4.
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.