Application
HSD17B4 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.Application
Western blot analysis in MCF-7,ZR-75-1,HepG2 cell line lysates (35ug/lane).| Product Name | HSD17B4 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Peroxisomal multifunctional enzyme type 2, MFE-2, 17-beta-hydroxysteroid dehydrogenase 4, 17-beta-HSD 4, D-bifunctional protein, DBP, Multifunctional protein 2, MPF-2, (3R)-hydroxyacyl-CoA dehydrogenase, 111n12, Enoyl-CoA hydratase 2, 3-alpha,7-alpha,12-al |
| Product description | The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. [provided by RefSeq].1) Canzian, F., et al. Hum. Mol. Genet. 19(19):3873-3884(2010) |
| Immunogen | This HSD17B4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-370 amino acids from the Central region of human HSD17B4. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | HSD17B4 |
|---|---|
| Alternative Names | Peroxisomal multifunctional enzyme type 2 MFE-2 17-beta-hydroxysteroid dehydrogenase 4 17-beta-HSD 4 D-bifunctional protein DBP Multifunctional protein 2 MPF-2 (3R)-hydroxyacyl-CoA dehydrogenase 111n12 Enoyl-CoA hydratase 2 3-alpha 7-alpha 12-al |
| Molecular Weight(MW) | 80 kDa |
Application
HSD17B4 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Application
Western blot analysis in MCF-7,ZR-75-1,HepG2 cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
