Application
Antibody used in WB on Human heart at 0.2-1 ug/ml.Application
Antibody used in IF on Mouse Spinal Cord at 1.3 ug/ml.| Product Name | HTR3E Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HTR3E, 5-HT3c1, MGC120035, MGC120036, MGC120037, 5-HT3E, 5-HT3-E |
| Product description | HTR3E belongs to the ligand-gated ion channel receptor superfamily. HTR3E is a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. An alternative splice variant has been described but its full length sequence has not been determined.1) Peters, J.A., Biochem. Soc. Trans. 32 (PT3), 547-552 (2004). |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HTR3E. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| HTR3E antibody can be used for detection of HTR3E by ELISA at 1:312500. HTR3E antibody can be used for detection of HTR3E by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | HTR3E |
|---|---|
| Alternative Names | HTR3E 5-HT3c1 MGC120035 MGC120036 MGC120037 5-HT3E 5-HT3-E |
| Molecular Weight(MW) | 53 kDa |
Application
Antibody used in WB on Human heart at 0.2-1 ug/ml.
Application
Antibody used in IF on Mouse Spinal Cord at 1.3 ug/ml.| Positive Control | 1) Cat. No. XBL-10407 - Fetal Heart Tissue Lysate |
|---|---|
| Application Notes | HTR3E antibody can be used for detection of HTR3E by ELISA at 1:312500. HTR3E antibody can be used for detection of HTR3E by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store HTR3E antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
