Application
Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).| Product Name | HTRA4 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Serine protease HTRA4, 3421-, High-temperature requirement factor A4, HTRA4 |
| Product description | This gene encodes a member of the HtrA family of proteases. The encoded protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging.1) Clausen, T., et al. Mol. Cell 10(3):443-455(2002) |
| Immunogen | This HTRA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-311 amino acids from the Central region of human HTRA4. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | HTRA4 |
|---|---|
| Alternative Names | Serine protease HTRA4 3421- High-temperature requirement factor A4 HTRA4 |
| Molecular Weight(MW) | 51 kDa |
Application
Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
