Application
Immunohistochemistry staining of IAPP in pancreas, islet of langerhans tissue using IAPP monoclonal Antibody.| Product Name | IAPP Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IAPP, Diabetes-associated peptide, Islet amyloid polypeptide, AMYLIN, IAP, Insulinoma amyloid peptide |
| Product description | Islet of insulinoma amyloid polypeptide (IAPP) is a 37 amino acids monomeric polypeptide isolated from pancreatic amyloid. It is commonly found in the islet of patients with diabetes mellitus type II and in insulinomas. IAPP selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. |
| Immunogen | IAPP monoclonal antibody was raised against a synthetic peptide corresponding to C-Terminus of IAPP (Human). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | IHC |
| IAPP antibody can be used in ELISA, and immunohistochemistry starting at 10 μg/mL.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Symbol | IAPP |
|---|---|
| Alternative Names | IAPP Diabetes-associated peptide Islet amyloid polypeptide AMYLIN IAP Insulinoma amyloid peptide |
| Tissue Specificity | Recognizes the islet amyloid polypeptide (amylin). Is of high affinity, and stains islet amyloid peptide in intra-cellular insulin granules, intra-cellular amyloid and extra-cellular islet amyloid. |
Application
Immunohistochemistry staining of IAPP in pancreas, islet of langerhans tissue using IAPP monoclonal Antibody.| Application Notes | IAPP antibody can be used in ELISA, and immunohistochemistry starting at 10 μg/mL.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | IAPP antibody should be stored long term (months) at -20 ˚C and short term (weeks) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | 0.09% sodium azide. |
