Application
Western blot analysis of lysed extracts from MDA cells using ICAM-1 (Ab-512).| Product Name | ICAM 1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | BB2, CD54, P3.58, ICA1, ICAM1 |
| Product description | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.1) Greenwood J, et al. (2003) J Immunol; 171 (4): 2099-2108. Zhou Z, et al. (2005) Eur J Pharmacol; 513 (1-2): 1-8. Chen YH, et al. (2001) J Cell Biochem; 82 (3): 512-521 |
| Immunogen | ICAM-1 (Ab-512) antibody was raised against a peptide sequence around aa. 510~514 (K-K-Y-R-L) derived from Human ICAM-1. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: 1:500~1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ICAM1 |
|---|---|
| Alternative Names | BB2 CD54 P3.58 ICA1 ICAM1 |
| Molecular Weight(MW) | 92 kDa |
| Tissue Specificity | This antibody detects endogenous level of total ICAM-1 protein. |
| Entrez Gene | 3383 |
|---|---|
| Protein Accession | NP_000192.2 |
Application
Western blot analysis of lysed extracts from MDA cells using ICAM-1 (Ab-512).| Application Notes | Western Blot: 1:500~1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
