Application
Antibody is used in Western blot to detect ICMT in T47D (left) and SK-BR-3 (right) tissue lysate| Product Name | ICMT Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Protein-S-isoprenylcysteine O-methyltransferase, Isoprenylcysteine carboxylmethyltransferase, Prenylated protein carboxyl methyltransferase, PPMT, Prenylcysteine carboxyl methyltransferase, pcCMT, ICMT, PCCMT |
| Product description | This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing results in two transcript variants encoding different isoforms.1) Bergo, M.O., et al., J. Clin. Invest. 113(4):539-550 (2004). |
| Immunogen | This ICMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-284 amino acids from the C-terminal region of human ICMT. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Symbol | ICMT |
|---|---|
| Alternative Names | Protein-S-isoprenylcysteine O-methyltransferase Isoprenylcysteine carboxylmethyltransferase Prenylated protein carboxyl methyltransferase PPMT Prenylcysteine carboxyl methyltransferase pcCMT ICMT PCCMT |
| Molecular Weight(MW) | 32 kDa |
Application
Antibody is used in Western blot to detect ICMT in T47D (left) and SK-BR-3 (right) tissue lysate| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
