ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. ID-2 may be an inhibitor of tissue-specific gene expression.1) The MGC Project TeamGenome Res. 14:2121-2127 (2004)
Immunogen
Id2 antibody was raised against a peptide sequence around aa.5~9 (S-P-V-R-S) derived from Human Id2.