IFITM1 Antibody: 9-27, CD225, IFI17, LEU13, DSPA2a, Interferon-induced transmembrane protein 1, Dispanin subfamily A member 2a
Product description
IFITM1 Antibody: IFITM1 (Interferon inducible transmembrane protein 1) is a member of the IFN-inducible transmembrane protein family. It is an essential mediator of interferon-gamma-induced antiproliferation and plays a role in the control of cell growth. IFITM1 is upregulated in several tumor types and may be useful as a tumor biomarker. Both mouse IFITM1 and IFITM3 are expressed on the cell surfaces of primordial germ cells in a developmentally-regulated manner. IFITM1 activity is required for primordial germ cell transit, and IFITM1 acts as a repulsive molecule by repelling non-IFITM1-expressing primordial germ cells from the mesoderm into the endoderm.1) Deblandre GA, Marinx OP, Evans SS, et al. Expression cloning of an interferon-inducible 17 kDa membrane protein implicated in the control of cell growth. J. Biol. Chem.1995; 270:23860-6.
Immunogen
IFITM1 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human IFITM1. The immunogen is located within the last 50 amino acids of IFITM1.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAWB
IFITM1 antibody can be used for detection of IFITM1 by Western blot at 2.5 - 5 μg/mL.:
Western blot analysis of IFITM1 in Jurkat cell lysate with IFITM1 antibody at (A) 2.5 and (B) 5 μg/mL.
Positive Control
1) Cat. No. 1205 - Jurkat Cell Lysate
Application Notes
IFITM1 antibody can be used for detection of IFITM1 by Western blot at 2.5 - 5 μg/mL.:
Additional Information
Form
Liquid
Storage Instructions
IFITM1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer
IFITM1 Antibody is supplied in PBS containing 0.02% sodium azide.