Application
Antibody used in WB on Human HepG2 cells at 1.25 ug/ml.Application
Antibody used in WB on Mouse testis and HeLa at 1:800 (Lanes: 1. 100 ug mouse testis lysate, 2. 100 ug HeLa cell lysate).| Product Name | IKBKG Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IKBKG, IP, IP1, IP2, FIP3, IPD2, NEMO, FIP-3, Fip3p, AMCBX1, ZC2HC9, IKK-gamma |
| Product description | Familial incontinentia pigmenti (IP) is a genodermatosis that segregates as an X-linked dominant disorder and is usually lethal prenatally in males . In affected females it causes highly variable abnormalities of the skin, hair, nails, teeth, eyes, and central nervous system. The prominent skin signs occur in 4 classic cutaneous stages: perinatal inflammatory vesicles, verrucous patches, a distinctive pattern of hyperpigmentation, and dermal scarring. Cells expressing the mutated X chromosome are eliminated selectively around the time of birth, so females with IP exhibit extremely skewed X-inactivation. Familial incontinentia pigmenti is caused by mutations in the NEMO gene and is here referred to as IP2, or 'classical' incontinentia pigmenti. Sporadic incontinentia pigmenti, the so-called IP1, which maps to Xp11, is categorized as hypomelanosis of Ito1) Hai, T., et al., (2006) J. Virol. 80 (9), 4227-4241. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IKBKG. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| IKBKG antibody can be used for detection of IKBKG by ELISA at 1:312500. IKBKG antibody can be used for detection of IKBKG by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | DogHuman |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | IKBKG |
|---|---|
| Alternative Names | IKBKG IP IP1 IP2 FIP3 IPD2 NEMO FIP-3 Fip3p AMCBX1 ZC2HC9 IKK-gamma |
| Molecular Weight(MW) | 48 kDa |
Application
Antibody used in WB on Human HepG2 cells at 1.25 ug/ml.
Application
Antibody used in WB on Mouse testis and HeLa at 1:800 (Lanes: 1. 100 ug mouse testis lysate, 2. 100 ug HeLa cell lysate).| Positive Control | 1) Cat. No. 1211 - HepG2 Cell Lysate |
|---|---|
| Application Notes | IKBKG antibody can be used for detection of IKBKG by ELISA at 1:312500. IKBKG antibody can be used for detection of IKBKG by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store IKBKG antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
