Application
Immunohistochemistry staining of IKBKG in pancreas tissue using IKBKG Antibody.| Product Name | IKBKG Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IKBKG, AMCBX1, FIP3, Fip3p, IkappaB kinase gamma, IKKgamma, IKK-gamma, NEMO, NF-kappa-B essential modifier, I-kappa-B kinase gamma-subunit, I-kappa-B kinase subunit gamma, IkB kinase gamma subunit, IKKAP1, Incontinentia pigmenti, IP2, IPD2, NF-kappa-B esse |
| Product description | Nuclear factor kappa B (NF-κB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-κB mediates the expression of a great variety of genes in response to extracellular stimuli. NF-κB is associated with IkB proteins in the cell cytoplasm, which inhibit NF-κB activity. The IkB kinase (IKKa and IKKb) phosphorylates IkB and mediates NF-κB activation. A novel molecule in the IKK complex was recently identified and termed IKKg/NEMO/FIP3/IKKAP1. IKKg interacts with IKKb and is required for the activation of IKK complex and NF-κB by LPS, PMA, TNF, and IL-1 stimulation. FIP3 was also shown to bind to RIP and NIK and to mediate TNF-induced NF-κB activation. |
| Immunogen | IKBKG antibody was raised against amino acids 385 - 399 of IKBKG (Human). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| IKBKG antibody can be used in ELISA, and immunohistochemistry starting at 2.5 μg/mL.: |
|
| Species Reactivity | DogGorillaHamsterHorseHumanMonkeyMouseRabbitRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | IKBKG |
|---|---|
| Alternative Names | IKBKG AMCBX1 FIP3 Fip3p IkappaB kinase gamma IKKgamma IKK-gamma NEMO NF-kappa-B essential modifier I-kappa-B kinase gamma-subunit I-kappa-B kinase subunit gamma IkB kinase gamma subunit IKKAP1 Incontinentia pigmenti IP2 IPD2 NF-kappa-B esse |
Application
Immunohistochemistry staining of IKBKG in pancreas tissue using IKBKG Antibody.| Application Notes | IKBKG antibody can be used in ELISA, and immunohistochemistry starting at 2.5 μg/mL.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store IKBKG antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.02% sodium azide. |
