Principal Names: Interleukin 20 receptor alpha(IL20RA); IL-20R1; ZcytoR7; ZCYTOR7; Cytokine receptor Class II member 8(CRF2-8); Official Gene Symbol: IL20RA Gene ID: 53832 (Human) Gene Map Locus: 6q22.33-q23.1 (Human) IL20RA,is a subunit of IL20R, a member of Cytokine Class II receptor super family. It consists of a central transmembrane domain and functionally induces IL20 and IL26 signaling in epithelial cells and keratinocytes. It associates with IL-20RB and forms a functional receptor complexfor IL20, IL19, and IL24. It also associates with IL-10RB and forms a unique heterodimeric functional receptor complex for IL-26. Upon ligand binding, it induces signaling through activation of STAT3 and STAT1. IL20RA is specifically expressed in skin suggesting a prominent role in growth and proliferation of keratinocytes.
Immunogen
IL - 20A Receptor antibody was raised against amino acids 159 - 175 of IL - 20A Receptor (Human).
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
FACSIHCWB
IL-20A Receptor antibody can be used in immunohistochemistry starting at 15 μg/mL.:
The amino acid sequence used as immunogen is 100% homologous in human and chimp, and 82% homologous in mouse and rat. Both the expect ~70 kD band and an unknown ~90 kD band are seen in A375 cell lysate and are blocked by the immunizing peptide. The ~ ...
Immunohistochemistry staining of IL-20A receptor in testis tissue using IL-20A receptor Antibody.
Application Notes
IL-20A Receptor antibody can be used in immunohistochemistry starting at 15 μg/mL.:
Additional Information
Form
Liquid
Storage Instructions
IL-20A Receptor antibody should be stored long term (months) at -20 ˚C and short term (weeks) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles.