Interleukin-22 receptor subunit alpha-2, IL-22 receptor subunit alpha-2, IL-22R-alpha-2, IL-22RA2, Cytokine receptor class-II member 10, Cytokine receptor family 2 member 10, CRF2-10, Cytokine receptor family type 2, soluble 1, CRF2-S1, Interleukin-22-bind
Product description
The protein encoded by this gene is a soluble class II
cytokine receptor. This protein has been shown to specifically bind
to interleukin 22 (IL22), block the interaction of IL22 with its
cell surface receptor, and thus inhibit IL22 activity. This protein
functions as an IL22 antagonist, and may be important in the
regulation of inflammatory response. Three alternatively spliced
transcript variants encoding distinct isoforms have been described.1) Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Immunogen
This IL22RA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-42 amino acids from the N-terminal region of human IL22RA2.
Western blot analysis in T47D cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.