The protein encoded by this gene is a subunit of the
receptor for IL23A/IL23. This protein pairs with the receptor
molecule IL12RB1/IL12Rbeta1, and both are required for IL23A
signaling. This protein associates constitutively with Janus kinase
2 (JAK2), and also binds to transcription activator STAT3 in a
ligand-dependent manner.1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Immunogen
This IL23R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 428-457 amino acids from the C-terminal region of human IL23R.
Western blot analysis in K562 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.