Interferon lambda receptor 1, IFN-lambda receptor 1, IFN-lambda-R1, Cytokine receptor class-II member 12, Cytokine receptor family 2 member 12, CRF2-12, Interleukin-28 receptor subunit alpha, IL-28 receptor subunit alpha, IL-28R-alpha, IL-28RA, Likely inte
Product description
The protein encoded by this gene belongs to the class II
cytokine receptor family. This protein forms a receptor complex
with interleukine 10 receptor, beta (IL10RB). The receptor complex
has been shown to interact with three closely related cytokines,
including interleukin 28A (IL28A), interleukin 28B (IL28B), and
interleukin 29 (IL29). The expression of all three cytokines can be
induced by viral infection. The cells overexpressing this protein
have been found to have enhanced responses to IL28A and IL29, but
decreased response to IL28B. Three alternatively spliced transcript
variants encoding distinct isoforms have been reported. [provided
by RefSeq].1) Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Immunogen
This IL28RA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 485-513 amino acids from the C-terminal region of human IL28RA.
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.