Application
Immunohistochemistry of ILPIP in human brain tissue with ILPIP antibody at 10 μg/mL.Application
Western blot analysis of ILPIP in human brain lysate with ILPIP antibody at (A) 1 and (B) 2 μg/mL.| Product Name | ILPIP Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ILPIP Antibody: PAPK, ILPIP, ILPIPA, ALS2CR2, CALS-21, PRO1038, STE20-related kinase adapter protein beta, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein, STRAD beta |
| Product description | ILPIP Antibody: ILPIP (ILP-interacting protein) has recently been shown to interact with XIAP, a member of the IAP (Inhibitor of Apoptosis) protein family. Together, these two proteins synergistically activate the TAK1/JNK1 signal transduction pathway, which acts to protect against the interleukin-1β converting enzyme of Fas-induced apotosis. This protein was independently isolated and characterized as polyploidy-associated protein kinase (PAPK), a member of the Ste20/germinal center kinase family that modulates cytoskeletal organization and cell survival, suggesting that its protective role may be a function of its kinase activity. Although two mRNA sequences have been isolated, only the shorter isoform has been observed.1) Sanna MG, Correia JS, Luo Y, et al. (2002) ILPIP, a novel anti-apototic protein that enhances XIAP-mediated activation of JNK and protection of apoptosis. J. Biol. Chem. 277:30454-62. |
| Immunogen | ILPIP antibody was raised against a synthetic peptide corresponding to amino acids near the center of human ILPIP. The immunogen is located within amino acids 280 - 330 of ILPIP. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIHC-PWB |
| ILPIP antibody can be used for the detection of ILPIP by Western blot at 1 to 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 10 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | STRADB |
|---|---|
| Alternative Names | ILPIP Antibody: PAPK ILPIP ILPIPA ALS2CR2 CALS-21 PRO1038 STE20-related kinase adapter protein beta Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein STRAD beta |
| Sequence Similarities | 2) Cat. No. 10-301 - Human Brain Tissue Slide |
Application
Immunohistochemistry of ILPIP in human brain tissue with ILPIP antibody at 10 μg/mL.
Application
Western blot analysis of ILPIP in human brain lysate with ILPIP antibody at (A) 1 and (B) 2 μg/mL.| Positive Control | 1) Cat. No. 1303 - Human Brain Tissue Lysate |
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| Application Notes | ILPIP antibody can be used for the detection of ILPIP by Western blot at 1 to 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 10 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | ILPIP antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | ILPIP Antibody is supplied in PBS containing 0.02% sodium azide. |
