Application
Immunohistochemistry staining of Insulin in pancreas tissue using Insulin monoclonal Antibody.| Product Name | Insulin Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | INS, IRDN, IDDM2, Preproinsulin, ILPR, Insulin, MODY10, Proinsulin |
| Product description | Recognizes the 51 amino acid (6 kDa) insulin polypeptide composed of A and B chains. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-peptide basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain acids. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as b-cell and tumor (insulinoma) markers). |
| Immunogen | Insulin monoclonal antibody was raised against purified Insulin coupled to bovine serum albumin (BSA) (Human). Hybridoma: Produced by the fusion between BALB/c mouse splenocytes and mouse myeloma SP2/0 cells after immunization with insulin from human pancr |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1, k |
| Host Species | Mouse |
| Tested Applications | ELISAIHCWB |
| WB:1:500~1:1000 IHC:1:50~1:200 ELISA:1:5000~20000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | INS |
|---|---|
| Alternative Names | INS IRDN IDDM2 Preproinsulin ILPR Insulin MODY10 Proinsulin |
Application
Immunohistochemistry staining of Insulin in pancreas tissue using Insulin monoclonal Antibody.| Application Notes | WB:1:500~1:1000 IHC:1:50~1:200 ELISA:1:5000~20000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store Insulin antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide. |
