Application
Immunohistochemistry staining of Insulin receptor in pancreas, islet of langerhans tissue using Insulin receptor Antibody.| Product Name | Insulin Receptor Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | INSR, CD220, ILP receptor, Insulin receptor, IR, HHF5, CD220 antigen |
| Product description | INSR is an insulin receptor type protein kinase. Binding of insulin to INSR stimulates glucose uptake. Two insulin receptor mRNA transcripts resulting from alternative splicing of exon 11 in the receptor gene are expressed in a highly regulated tissue-specific fashion. Mutations in the INSR gene contribute to diseases, including of various forms of insulin resistance, insulin-resistant diabetes mellitus, noninsulin-dependent diabetes mellitus (NIDDM), Rabson-Mendenhall syndrome and Leprechaunism (Donohue Syndrome). |
| Immunogen | Insulin Receptor antibody was raised against a peptide located near the internal domain of Insulin Receptor (Human). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IHC |
| Insulin Receptor antibody can be used in ELISA starting at 1:10000, Western Blot starting at 1:500 - 1:2000, and immunohistochemistry starting at 1:200 - 1:400.: |
|
| Species Reactivity | HumanMonkey |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | INSR |
|---|---|
| Alternative Names | INSR CD220 ILP receptor Insulin receptor IR HHF5 CD220 antigen |
| Tissue Specificity | BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Application
Immunohistochemistry staining of Insulin receptor in pancreas, islet of langerhans tissue using Insulin receptor Antibody.| Application Notes | Insulin Receptor antibody can be used in ELISA starting at 1:10000, Western Blot starting at 1:500 - 1:2000, and immunohistochemistry starting at 1:200 - 1:400.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Insulin Receptor antibody should be stored long term (months) at -80 ˚C and short term (days) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.1% sodium azide. |
