Application
Western blot analysis in Ramos cell line lysates (35ug/lane).| Product Name | IQCB1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | This gene encodes a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. The encoded protein has a central coiled-coil region and two calmodulin-binding IQ domains. It is localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells. The protein is thought to play a role in ciliary function. Defects in this gene result in Senior-Loken syndrome type 5. Alternative splicing results in multiple transcript variants.1) Hildebrandt, F., et al. J. Am. Soc. Nephrol. 20(1):23-35(2009) |
| Immunogen | This IQCB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 384-411 amino acids from the Central region of human IQCB1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000 | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | IQCB1 |
|---|---|
| Alternative Names | IQ calmodulin-binding motif-containing protein 1 Nephrocystin-5 p53 and DNA damage-regulated IQ motif protein PIQ IQCB1 KIAA0036 NPHP5 |
| Molecular Weight(MW) | 69 kDa |
Application
Western blot analysis in Ramos cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
