Application
Immunohistochemistry staining of IQWD1 in skeletal muscle tissue using IQWD1 Antibody.| Product Name | IQWD1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Principal Names: Nuclear receptor Interacting Protein (NRIP); IQ motif and WD repeats 1 (IQWD1) Official Gene Symbol: IQWD1 Gene ID: 55827 (Human) Gene Map Locus: 1q24.2 (Human) WD-repeat proteins are a large family of eukaryotic proteins coordinating multi-protein complex assemblies and their role has been implicated in multiple cellular processes including signal transduction, transcriptional regulation, cell cycle control and apoptosis. NRIP is a novel 860a.a nuclear protein consisting of seven conserved WD40 domains and one NLS motif. It binds to androgen and glucocorticoid receptors and up regulates their transcriptional activity, thereby functioning as a nuclear receptor coactivator. Role of NRIP has been implicated in cell growth and also in cervical and prostrate cancer thus indicating a therapeutic intervention. Northern Blot analysis detected a high expression of NRIP in skeletal muscle and testis and low expression in heart, prostrate and adrenal gland. |
| Immunogen | A portion of amino acids 800-850 of human NRIP. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| IQWD1 antibody can be used in ELISA, Western Blot, and immunohistochemistry starting at 10 - 20 μg/mL. | |
| Species Reactivity | DogHumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | DCAF6 |
|---|---|
| Alternative Names | DCAF6 ARCAP PC326 IQ motif and WD repeats 1 RP4-745I14.1 IQWD1 MSTP055 NRIP |
| Tissue Specificity | The amino acid sequence used is 100% homologous in human (isoforms a and b), mouse, rat and dog, 88% homologous in zebrafish and 82% homologous in xenopus. |
Application
Immunohistochemistry staining of IQWD1 in skeletal muscle tissue using IQWD1 Antibody.| Application Notes | IQWD1 antibody can be used in ELISA, Western Blot, and immunohistochemistry starting at 10 - 20 μg/mL. |
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| Form | Liquid |
|---|---|
| Storage Instructions | IQWD1 antibody can be stored short term 4 ˚C. For long term storage aliquot and store at -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.2% gelatin, 0.05% sodium azide. |
