Application
Western blot analysis in CEM cell line lysates (35ug/lane).| Product Name | ITGB2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Integrin beta-2, Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta, Complement receptor C3 subunit beta, CD18, ITGB2, CD18, MFI7 |
| Product description | The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene.1) Gjelstrup, L.C., et al. J. Immunol. 185(7):4154-4168(2010) |
| Immunogen | This ITGB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 272-300 amino acids from the N-terminal region of human ITGB2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ITGB2 |
|---|---|
| Alternative Names | Integrin beta-2 Cell surface adhesion glycoproteins LFA-1/CR3/p150 95 subunit beta Complement receptor C3 subunit beta CD18 ITGB2 CD18 MFI7 |
| Molecular Weight(MW) | 85 kDa |
Application
Western blot analysis in CEM cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
