Application
Western blot analysis of JAKMIP1 in rat brain tissue lysate with JAKMIP1 antibody at (A) 1 and (B) 2 μg/mL| Product Name | JAKMIP1 Antibody |
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| Antibody Type | Primary Antibodies |
| Antigen Alias | JAKMIP1 Antibody: JAMIP1, MARLIN1, Gababrbp, GABABRBP, JAMIP1, Janus kinase and microtubule-interacting protein 1, GABA-B receptor-binding protein, Marlin-1 |
| Product description | JAKMIP1 Antibody: JAKMIP1, also known as Marlin-1, is a highly-conserved vertebrate-specific microtubule-associated protein that plays a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements. JAKMIP1 is expressed predominantly in neuronal and lymphoid cells and colocalizes with microtubules. Multiple isoforms of JAKMIP1 are known to exist: isoforms 1 and 5 are also expressed in liver, lung and skeletal muscle, while isoforms 2-4 are specifically expressed in brain and retina. JAKMIP1 participates in polarized secretion in lymphocytes and it has been suggested to be a novel effector memory gene restraining T cell-mediated cytotoxicity. Dysregulation of JAKMIP1 gene expression is associated with genetic conditions linked to autism in humans.1) Costa V, Conte I, Ziviello C, et al. Identification and expression analysis of novel Jakmip1 transcripts. Gene 2007; 402:1-8. |
| Immunogen | Rabbit polyclonal JAKMIP1 antibody was raised against a 16 amino acid peptide near the center of human JAKMIP1. The immunogen is located within amino acids 260 - 310 of JAKMIP1. |
| Clonality | Polyclonal |
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| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| JAKMIP1 antibody can be used for detection of JAKMIP1 by Western blot at 1 - 2 μg/mL.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | JAKMIP1 |
|---|---|
| Alternative Names | JAKMIP1 Antibody: JAMIP1 MARLIN1 Gababrbp GABABRBP JAMIP1 Janus kinase and microtubule-interacting protein 1 GABA-B receptor-binding protein Marlin-1 |
| Molecular Weight(MW) | Predicted: 69 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Bovine: (100%) |
| Tissue Specificity | Multiple isoforms of JAKMIP1 are known to exist. JAKMIP1 antibody is predicted to not cross-react with JAKMIP2. |
Application
Western blot analysis of JAKMIP1 in rat brain tissue lysate with JAKMIP1 antibody at (A) 1 and (B) 2 μg/mL| Positive Control | 1) Cat. No. 1463 - Rat Brain Tissue Lysate |
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| Application Notes | JAKMIP1 antibody can be used for detection of JAKMIP1 by Western blot at 1 - 2 μg/mL.: |
| Form | Liquid |
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| Storage Instructions | JAKMIP1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | JAKMIP1 Antibody is supplied in PBS containing 0.02% sodium azide. |
