| Product Name | Janus kinase 2 (phospho Tyr372) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Janus kinase 2-pY372-phospho specific, Janus kinase 2, |
| Product description | Janus Kinase 2 (JAK2) is essential for signaling thorough a variety of cytokine receptors. Phosphorylation of JAK is essential for downstream signaling. JAK kinases are known to phosphorylate several substrate including members of the STAT family of proteins1) Issam McDoom, Xianyue Ma, Annet Kirabo, Kuang-Yung Lee, David A. Ostrov and Peter P. Sayeski., Identification of Tyrosine 972 as a Novel Site of Jak2 Tyrosine Kinase Phosphorylation and Its Role in Jak2 Activation., Biochemistry, 2008, 47 (32), pp 8326-8334 |
| Immunogen | A synthetic peptide corresponding to the pY372 region. |
| Modification | p-Tyr372 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| ELISA, Western (immuno) blotting, Immunostaining (in testing): |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | JAK2 |
|---|---|
| Alternative Names | Janus kinase 2-pY372-phospho specific Janus kinase 2 |
| Application Notes | ELISA, Western (immuno) blotting, Immunostaining (in testing): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
