Application
Antibody used in WB on Human Jurkat 1 ug/ml.| Product Name | JMJD2C Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | JMJD2C, FLJ25949, GASC1, JHDM3C, KDM4C, KIAA0780, bA146B14.1, JMJD2C, TDRD14C |
| Product description | JMJD2C is a member of the Jumonji domain 2 (JMJD2) family. It contains one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma.This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma.1) Katoh, Y. (2007) Int. J. Mol. Med. 20 (2), 269-273. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human JMJD2C. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| JMJD2C antibody can be used for detection of JMJD2C by ELISA at 1:62500. JMJD2C antibody can be used for detection of JMJD2C by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | KDM4C |
|---|---|
| Alternative Names | JMJD2C FLJ25949 GASC1 JHDM3C KDM4C KIAA0780 bA146B14.1 JMJD2C TDRD14C |
| Molecular Weight(MW) | 120 kDa |
Application
Antibody used in WB on Human Jurkat 1 ug/ml.| Positive Control | 1) Cat. No. 1211 - HepG2 Cell Lysate |
|---|---|
| Application Notes | JMJD2C antibody can be used for detection of JMJD2C by ELISA at 1:62500. JMJD2C antibody can be used for detection of JMJD2C by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store JMJD2C antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
