Application
Immunohistochemistry of KANK2 in human kidney tissue with KANK2 antibody at 2.5 μg/ml.Application
Immunofluorescence of KANK2 in human kidney tissue with KANK2 antibody at 20 μg/ml.Application
Western blot analysis of KANK2 in mouse brain tissue lysate with KANK2 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.| Product Name | KANK2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KANK2 Antibody: SIP, MXRA3, ANKRD25, KIAA1518, SIP, KN motif and ankyrin repeat domain-containing protein 2, Ankyrin repeat domain-containing protein 25 |
| Product description | KANK2 Antibody: Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization. KANK2 (KN motif and ankyrin repeat domain-containing protein 2), was initially identified as a steroid receptor coactivator (SRC) interacting protein (SIP) that could sequester steroid receptor coactivators in the cytoplasm. More recent experiments have shown that while KANK2 is widely expressed, in kidney podocytes, KANK2 localizes to foot processes, suggesting that KANK2 may contribute to controlling actin dynamics in podocyte foot processes.1) Zhu Y, Kakinuma N, Wang Y, et al. Kank proteins: a new family of ankyrin-repeat domain containing proteins. Biochim. Biophys. Acta 2008; 1780:128-33. |
| Immunogen | KANK2 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human KANK2 . The immunogen is located within the last 50 amino acids of KANK2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| KANK2 Antibody can be used for detection of KANK2 by Western blot at 1 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | KANK2 |
|---|---|
| Alternative Names | KANK2 Antibody: SIP MXRA3 ANKRD25 KIAA1518 SIP KN motif and ankyrin repeat domain-containing protein 2 Ankyrin repeat domain-containing protein 25 |
| Molecular Weight(MW) | Predicted: 95 kDa Observed: 102 kDa |
| Sequence Similarities | 2) Cat. No. 10-401 - Human Kidney Tissue Slide |
| Tissue Specificity | Two alternatively spliced transcript variants encoding different isoforms have been identified. |
Application
Immunohistochemistry of KANK2 in human kidney tissue with KANK2 antibody at 2.5 μg/ml.
Application
Immunofluorescence of KANK2 in human kidney tissue with KANK2 antibody at 20 μg/ml.
Application
Western blot analysis of KANK2 in mouse brain tissue lysate with KANK2 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.| Positive Control | 1) Cat. No. 1403 - Mouse Brain Tissue Lysate |
|---|---|
| Application Notes | KANK2 Antibody can be used for detection of KANK2 by Western blot at 1 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | KANK2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | KANK2 Antibody is supplied in PBS containing 0.02% sodium azide. |
