Application
Immunohistochemistry of KANK3 in human kidney tissue with KANK3 antibody at 2.5 μg/ml.Application
Western blot analysis of KANK3 in A431 cell lysate with KANK3 antibody at (A) 1 and (B) 2 μg/mL.| Product Name | KANK3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KANK3 Antibody: ANKRD47, ANKRD47, KN motif and ankyrin repeat domain-containing protein 3, Ankyrin repeat domain-containing protein 47 |
| Product description | KANK3 Antibody: Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization. Like other members of the KANK family, KANK3 (KN motif and ankyrin repeat domain-containing protein 3), is thought to play a role in the formation of actin stress fibers. In zebrafish, the homolog of KANK3 interacts with the adaptor protein Numb, a protein implicated in multiple basic cellular processes, and is essential for epidermal integrity and neurulation, suggesting that KANK3 may play a similar role in higher organisms.1) Zhu Y, Kakinuma N, Wang Y, et al. Kank proteins: a new family of ankyrin-repeat domain containing proteins. Biochim. Biophys. Acta 2008; 1780:128-33. |
| Immunogen | KANK3 antibody was raised against an 18 amino acid peptide near the amino terminus of human KANK3 . The immunogen is located within amino acids 50 - 100 of KANK3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIHC-PWB |
| KANK3 Antibody can be used for detection of KANK3 by Western blot starting at 1 μg/mL.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | KANK3 |
|---|---|
| Alternative Names | KANK3 Antibody: ANKRD47 ANKRD47 KN motif and ankyrin repeat domain-containing protein 3 Ankyrin repeat domain-containing protein 47 |
| Molecular Weight(MW) | Predicted: 90 kDa Observed: 100 kDa |
| Sequence Similarities | 2) Cat. No. 10-401 - Human Kidney Tissue Slide |
| Tissue Specificity | Two alternatively spliced transcript variants encoding different isoforms have been identified. |
Application
Immunohistochemistry of KANK3 in human kidney tissue with KANK3 antibody at 2.5 μg/ml.
Application
Western blot analysis of KANK3 in A431 cell lysate with KANK3 antibody at (A) 1 and (B) 2 μg/mL.| Positive Control | 1) Cat. No. 1202 - A431 Cell Lysate |
|---|---|
| Application Notes | KANK3 Antibody can be used for detection of KANK3 by Western blot starting at 1 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | KANK3 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | KANK3 Antibody is supplied in PBS containing 0.02% sodium azide. |
