Microtubules, polymers of alpha and beta tubulin subunits,
form the mitotic spindle of a dividing cell and help to organize
membranous organelles during interphase. Katanin is a heterodimer
that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa
accessory protein (p80 subunit B 1). The p60 subunit acts to sever
and disassemble microtubules, while the p80 subunit targets the
enzyme to the centrosome. This gene encodes the p80 subunit. This
protein is a member of the AAA family of ATPases. [provided by
RefSeq].1) Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :
Immunogen
This KATNA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-85 amino acids from the N-terminal region of human KATNA1.
Western blot analysis in 293 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.