Application
Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).| Product Name | KCNA5 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Potassium voltage-gated channel subfamily A member 5, HPCN1, Voltage-gated potassium channel HK2, Voltage-gated potassium channel subunit Kv15, KCNA5 |
| Product description | Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion. This gene is intronless, and the gene is clustered with genes KCNA1 and KCNA6 on chromosome 12. [provided by RefSeq].1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) |
| Immunogen | This KCNA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 508-536 amino acids from the C-terminal region of human KCNA5. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | KCNA5 |
|---|---|
| Alternative Names | Potassium voltage-gated channel subfamily A member 5 HPCN1 Voltage-gated potassium channel HK2 Voltage-gated potassium channel subunit Kv15 KCNA5 |
| Molecular Weight(MW) | 67 kDa |
Application
Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
