The Shaker gene family of Drosophila encodes components of
voltage-gated potassium channels and is comprised of four
subfamilies. Based on sequence similarity, this gene is similar to
one of these subfamilies, namely the Shaw subfamily. The protein
encoded by this gene belongs to the delayed rectifier class of
channel proteins and is an integral membrane protein that mediates
the voltage-dependent potassium ion permeability of excitable
membranes. Three transcript variants encoding three different
isoforms have been found for this gene.1) Wang, Z., et al. J. Gen. Physiol. 133(4):361-374(2009)
Immunogen
This KCNC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 544-573 amino acids from the C-terminal region of human KCNC2.
Western blot analysis in mouse kidney tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.