The Shaker gene family of Drosophila encodes components of
voltage-gated potassium channels and is comprised of four
subfamilies. Based on sequence similarity, this gene is similar to
the Shaw subfamily. The protein encoded by this gene belongs to the
delayed rectifier class of channel proteins and is an integral
membrane protein that mediates the voltage-dependent potassium ion
permeability of excitable membranes. It generates atypical
voltage-dependent transient current that may be important for
neuronal excitability. Multiple transcript variants have been found
for this gene.1) Mosing, M.A., et al. Twin Res Hum Genet 13(4):398-403(2010)
Immunogen
This KCNC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 518-546 amino acids from the C-terminal region of human KCNC4.
Western blot analysis in 293 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.