Voltage-gated potassium (Kv) channels represent the most
complex class of voltage-gated ion channels from both functional
and structural standpoints. Their diverse functions include
regulating neurotransmitter release, heart rate, insulin secretion,
neuronal excitability, epithelial electrolyte transport, smooth
muscle contraction, and cell volume. This gene encodes a member of
the potassium channel, voltage-gated, isk-related subfamily. This
member is a small integral membrane subunit that assembles with the
KCNH2 gene product, a pore-forming protein, to alter its function.
This gene is expressed in heart and muscle and the gene mutations
are associated with cardiac arrhythmia.1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Immunogen
This KCNE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-107 amino acids from the C-terminal region of human KCNE2.
Western blot analysis in A549 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.