This gene encodes a member of the family of voltage-gated
potassium (Kv) channel-interacting proteins (KCNIPs), which belongs
to the recoverin branch of the EF-hand superfamily. Members of the
KCNIP family are small calcium binding proteins. They all have
EF-hand-like domains, and differ from each other in the N-terminus.
They are integral subunit components of native Kv4 channel
complexes. They may regulate A-type currents, and hence neuronal
excitability, in response to changes in intracellular calcium.
Multiple alternatively spliced transcript variants encoding
distinct isoforms have been identified from this gene. [provided by
RefSeq].1) Foeger, N.C., et al. J. Biol. Chem. 285(43):33413-33422(2010)
Immunogen
This KCNIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-78 amino acids from the N-terminal region of human KCNIP2.
Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.