This gene is a member of the KCNQ potassium channel gene
family that is differentially expressed in subregions of the brain
and in skeletal muscle. The protein encoded by this gene yields
currents that activate slowly with depolarization and can form
heteromeric channels with the protein encoded by the KCNQ3 gene.
Currents expressed from this protein have voltage dependences and
inhibitor sensitivities in common with M-currents. They are also
inhibited by M1 muscarinic receptor activation. Multiple transcript
variants encoding different isoforms have been found for this gene.1) Bailey, S.D., et al. Diabetes Care (2010) In press :
Immunogen
This KCNQ5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 781-809 amino acids from the C-terminal region of human KCNQ5.
Western blot analysis in mouse heart tissue lysates (35ug/lane).
Application
Western Blot at 1:1000 dilution + human skeletal muscle lysate Lysates/proteins at 20 ug per lane.
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.