DNA-binding protein involved in S phase checkpoint control-coupled apoptosis by mediating TP53/p53-induced apoptosis. Has the ability to inhibit DNA synthesis and S phase arrest coupled to apoptosis. Has affinity to both double-and single-stranded DNA.1) Cho, Y.J., et al. Proc. Natl. Acad. Sci. U.S.A. 105(14):5396-5401(2008)
Immunogen
This KILLIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-163 amino acids from the C-terminal region of human KILLIN.
Western blot analysis in MDA-MB435 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.