Application
Western blot analysis of KLRA3 in mouse brain tissue lysate with KLRA3 antibody at 2 μg/mL.| Product Name | KLRA3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | KLRA3 Antibody: KLRA3 (also known as Ly49C) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA3 is thought to be an inhibitory receptor, recognizing peptide -receptive H-2Kb.1) Gosselin P, Lusignan Y, Brennan J, et al. The NK2.1 receptor is encoded by Ly-49C and its expression is regulated by MHC class I alleles. Int. Immunol.1997; 533-40. |
| Immunogen | KLRA3 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of mouse KLRA3. The immunogen is located within the last 50 amino acids of KLRA3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| KLRA3 antibody can be used for detection of KLRA3 by Western blot at 2 μg/mL. | |
| Species Reactivity | MouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Klra3 |
|---|---|
| Alternative Names | KLRA3 Antibody: 5E6 Nk2 Nk-2 Ly49c Nk2.1 NK-2.1 Ly-49c Ly49C Killer cell lectin-like receptor 3 5E6 |
| Tissue Specificity | This antibody may cross-react with other LY49 receptors. |
Application
Western blot analysis of KLRA3 in mouse brain tissue lysate with KLRA3 antibody at 2 μg/mL.| Positive Control | 1) Cat. No. 1403 - Mouse Brain Tissue Lysate |
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| Application Notes | KLRA3 antibody can be used for detection of KLRA3 by Western blot at 2 μg/mL. |
| Form | Liquid |
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| Storage Instructions | KLRA3 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | KLRA3 Antibody is supplied in PBS containing 0.02% sodium azide. |
